Mega doses of vitamin E can slow the mild and moderate Alzheimer's disease in a way that corresponds scales for sale to more than half a year of the launch of the incurable disease. It hopeful but also controversial outcome tops the latest issue of the medical journal JAMA.
Alzheimer's is a disease that currently has no cure. However, there are a number scales for sale of medicines with moderate power is considered to relieve the symptoms so that they appear later and prolongs the time that the patient himself can cope with things like financial planning, prepare a meal, getting dressed or taking a bath.
Now, the largest experimental study involving patients scales for sale with mild to moderate Alzheimer's that vitamin E in mega doses of 1340 milligrams per day in a significant scales for sale way can slow the symptoms of 19 percent per year. This corresponded to an average scales for sale of over six months of disease scales for sale progression during the two years and four months of the study.
The study included 613 patients at 14 health centers in the United States. Patients were divided into four groups that received either only vitamin E or only drug with the active ingredient memantine. A third group received a combination of both, while a fourth group received placebo.
The result after 2.3 years of follow up was that those who received vitamin E increased its value by 19 percent on the so-called ADCS-ADL scale that measures the ability to everyday scales for sale activities. Neither memantine alone or in combination with vitamin E showed such an effect.
"A loss of this magnitude can be translated scales for sale into either a complete loss of self to be able to dress or take a bath without help, or any of the three corresponding abilities," the authors write.
- Scientists have put a tremendous job and got the most effect on the vitamins which are startling and new. It's not a cure by any means but still hopeful. For the economy, it is also very interesting about the need for hospitalization can reduce a little later process scales for sale of the disease. It could mean that more people can live at home for a little longer, says professor and Alzheimer's researcher Bengt Winblad, Karolinska Institute.
He argues that the result is in line with developments in Alzheimer's treatment that is towards more medical food, ie food that contains more of certain vitamins such as C, D and E, certain minerals and a healthy balance of fats like Omega-3 and Omega-6.
Mega doses of vitamin E have never been common in Swedish Alzheimer's care and was abandoned almost entirely in the U.S. since a large meta-study in 2005 warned of an increased mortality of such high doses of vitamin E. The screening, however, cover groups other than Alzheimer's patients who through his illness still has a significantly shortened mean survival. According scales for sale to the new study, there are no such risks and instead seems the positive effects strongly considered in this population.
Memantine, scales for sale which in this study was much less effective than vitamin E, given in Sweden at a later stage of the disease when its effect is greater. The researchers behind the new study emphasizes that mega doses of vitamin E has not been shown to have any positive effect on cognitive abilities in healthy, nor in patients with mild cognitive impairment. It is precisely in the group with mild to moderate scales for sale Alzheimer's disease as the effect is clear.
In a scientific commentary in JAMA, the study may praise for its implementation by Denis Evans at Rush University who however finds that Alzheimer's is and remains an extremely intractable disease that affects millions of people in all developed countries. "A shift toward a greater emphasis on prevention seems necessary."
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